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Mild and moderate dry eyes are treated with eye drops. When the production of tears is severely impacted, eye drops no longer work. Your dry eye condition becomes severe and chronic.

Suppose you’ve been living with dry eye disease, in addition to the pain. In that case, it can have a significant and even debilitating effect on your vision and quality of life. You don’t have to just live with it. Ignoring your symptoms could lead to severe eye damage, such as a corneal ulcer or impaired vision. Severe cornea damage can lead to cornea transplantation.

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Customer Stories

Severe Chronic Dry Eye Syndrome- Relief using TheraLife Eye.

‘Tis the season to give thanks!  I certainly give mine for TheraLife!  I cannot believe I am getting down to only two to three or four capsules a day.  One in the morning seems to last all day.  How amazing is that?

I have very severe dry eyes, and used eye drops constantly with no results.  First time I tried TheraLife Eye, I took it for 2 weeks and quit.  This time, under the gentle guidance of Dr. Yang, I took TheraLife Eye capsules for one month, and my eyes feel normal again.  I gradually decreased the TheraLife Eye dosage – now I only take 2-4 capsules per day. 

I will make an appintment with my ophthalmologist for check-up and he says my eyes are doing so well,

EM,   CA

For more customers stories

What Is Severe Dry Eyes?

It is related to a problem with the tears which lubricate the eye surface.

The causes of this dry eye are due to:

  • Tear quantity: Tear production decrease with age, hormonal changes, environmental factors like dry air or wind. Without enough tears, your eyes can feel painfully itchy or gritty. Eye drops can compensate for the lack of tears temporarily.
  • When eye drops are no longer sufficient, oral dry eye treatment becomes the dry eye treatment of choice.
  • Tear quality: Tears are made up of water, mucous, and oil. Suppose there are deficiencies in any of these three aspects. In that case, your tears may evaporate too quickly or fail to spread adequately over the eye.

If your symptoms are chronic and disrupt your daily life, your dry eye may be considered moderate or severe.

Causes

If you’re feeling burning dry eyes with blurry vision, you’re not alone. About one-third of people with dry eyes experience symptoms of severe dry eyes.  And most cases—about 86%—are related to meibomian gland dysfunction (MGD). The meibomian glands are located on the edges of your eyelids. The meibomian glands are where the oil layer of tears is made, and if they’re clogged or not working correctly.

Dry eyes are more common among older people and especially women. Dry eyes can also be caused by contact lens wearing and some medications. Medical conditions that cause severe dry eyes including:

  • Diabetes
  • Autoimmune disorders including:
  • Rosacea – people with facial rosacea almost always get ocular rosacea
  • Thyroid conditions – either hyper and hypothyroid
  • Vitamin A deficiency

LASIK surgery.  Dry eye is prevalent following LASIK surgery and can worsen if a person already has symptoms, even mild ones, before surgery. This kind of symptoms typcailly resolves within six to 12 months of surgery, but for some people, it becomes chronic.

Risks

Left untreated, you’re in for more than just discomfort from severe dry eye.

Corneal Ulcer (Keratitis)

In severe cases, dry eye can lead to a corneal ulcer, also known as keratitis. Symptoms include:

  • Severe pain and redness in the eye
  • The sensation of a foreign object in your eye
  • A white spot on your cornea that may not be visible in the mirror
  • Eye discharge
  • Blurry vision
  • Light Sensitivity – Photophobia
Corneal Abrasion or Erosion

corneal abrasion is a scratch on your eye, while corneal erosion is when the layer of cells on your cornea loosens. Both can be caused by dry eyes and made worse by rubbing your eyes.

Eye doctors can advise on proper treatment, including eye drops or even surgery in severe cases.

Visual Symptoms and Quality of Life Impact

Dry eye may lead to light sensitivity, eye pain, headaches, blurred or foggy vision, and glare. These symptoms, along with the discomfort of dry eye, can affect a person’s ability to work and simply enjoy life.

A group of researchers found people over 40 years old with dry eye symptoms reported significant difficulty with many tasks, including:

  • Using stairs
  • Reading the newspaper
  • Cooking
  • Recognizing friends
  • Watching TV
  • Driving at night

Research shows that all of this combined may take a toll on your mental health.

Treatment

Your eye doctors can assess your dry eye with a comprehensive eye exam that includes a thorough discussion of symptoms with you.

Based on your exam, your doctor will suggest a course of treatment. Keep in mind that it could take a few months to fully address your symptoms and provide sufficient relief.

Your doctor may begin by suggesting treatments that include:

  • Over-the-counter artificial tears (eye drops)
  • At-home warm compress and gentle eyelid massage
  • Running a humidifier
  • Taking Omega-3 supplements and adding more fish to your diet
  • Eye hygiene if your dry eye is associated with inflammation of the eyelid known as blepharitis

Conventional Treatments

  • Anti-inflammatory prescription eye drops, including Xiidra, Restasis, Lotemax Gel. And oral antibiotic such as tetracycline, azithromycin.
  • Various in-office treatments to gently and effectively express blocked meibomian glands. Treatment recommendations might include:
    • Thermal compression, such as LipiFlow
    • Intense pulsed light therapy
    • Radiofrequency treatment
    • Debridement scaling-manually expressing the meibomian oil glands to unclog. Special forceps, Q-tips are used to push on the eyelids.
    • Intraductal meibomian probing – when none of those as mentioned above methods work to unclog oil glands.

If dry eye is still causing severe discomfort and no inflammation, a doctor may suggest punctal plugs. About the size of a grain of rice, these tiny devices are inserted into the puncta of the eye, blocking tears from draining away. This can keep the eye’s surface much more comfortable.

What to do next ?

If you’re feeling the debilitating effects of dry eye, you don’t have to deal with it alone. Call us toll-free and talk to a doctor.

1-877-917-1989. Relief is on the way.

Frequently Asked Questions

Can anything be done for severe dry eyes?

For severe chronic dry eyes, eye doctors often prescribe prescription eye drops like Restasis, Xiidra, and more.  TheraLife’s all natural oral dry eye treatment also works to relieve severe dry eyes, in combination with fish oil, warm compress and eyelid cleansing.  This combination allow you to recover faster without the use of steroid medications.  TheraLife protocol is often used in conjunction with prescription eye drops.

What diseases cause severe dry eyes?

Autoimmune diseases cause severe dry eyes, especially Sjogren’s Syndrome where the body attacks its own cells that produce moisture.  Other autoimmune diseases include Rheumatoid  Arthritis, Lupus, Hashimoto’s Thyroiditis, Graves Disease, Ocular Rosacea, and Uveitis.

How do you live with severe dry eyes?

People live with severe dry eyes by taking the TheraLife Eye capsules, Omega 3 fish oil, warm compress, and eyelid cleansing.  Sometimes autologous serum drops are prescribed to add more moisture that is compatible with your own tears.  You can also get LipiFlow and IPL to unclog your oil glands.

Conclusion

In conclusion, dry eye is a multifactorial disease of the tears and the ocular surface, a system formed by several structures working together to protect the eye from excessive environmental and biological stress. It is therefore critical to treat the main pathogenic mechanism(s) involved in Dry Eye Disease and to address also the secondary mechanisms that, if not appropriately controlled, might contribute to perpetuate the vicious circle of Dry Eye Disease. A proper and adaptable treatment will improve the ocular surface inducing a relief from symptoms and an effective improvement of the quality of life.

References

Aggarwal et al., 2019  S. Aggarwal, C. Colon, A. Kheirkhah, P. Hamrah Efficacy of autologous serum tears for treatment of neuropathic corneal pain Ocul. Surf., 17 (2019), pp. 532-539

Aggarwal, A. Kheirkhah, B.M. Cavalcanti, A. Cruzat, C. Colon, E. Brown, D. Borsook, H. Pruss, P. Hamrah Autologous serum tears for treatment of photoallodynia in patients with corneal neuropathy: efficacy and evaluation with in vivo confocal microscopy Ocul. Surf., 13 (2015), pp. 250-262

Aketa, M. Shinzawa, M. Kawashima, M. Dogru, S. Okamoto, K. Tsubota, J. Shimazaki Efficacy of plate expression of meibum on tear function and ocular surface findings in meibomian gland disease Eye Contact Lens, 45 (2019), pp. 19-22

Ang, M. Baskaran, R.M. Werkmeister, J. Chua, D. Schmidl, V. Aranha Dos Santos, G. Garhofer, J.S. Mehta, L. Schmetterer Anterior segment optical coherence tomography Prog. Retin. Eye Res., 66 (2018), pp. 132-156

Anitua, F. Muruzabal, M. de la Fuente, J. Merayo, J. Duran, G. Orive Plasma rich in growth factors for the treatment of ocular surface diseases Curr. Eye Res., 41 (2016), pp. 875-882

Anitua, F. Muruzabal, A. Tayebba, A. Riestra, V.L. Perez, J. Merayo-Lloves, G. Orive Autologous serum and plasma rich in growth factors in ophthalmology: preclinical and clinical studies Acta Ophthalmol., 93 (2015), pp. e605-614

Arita, M. Kawashima, M. Ito, K. Tsubota Clinical safety and efficacy of vitamin D3 analog ointment for treatment of obstructive meibomian gland dysfunction BMC Ophthalmol., 17 (2017), p. 84Arita, T. Mizoguchi, M. Kawashima, S. Fukuoka, S. Koh, R. Shirakawa, T. Suzuki, N. Morishige Meibomian gland dysfunction and dry eye are similar, but different based on a population-based study (Hirado-Takushima study) in Japan Am. J. Ophthalmol., 207 (2019), pp. 410-418

Ayaki, M. Kawashima, K. Negishi, T. Kishimoto, M. Mimura, K. Tsubota Sleep and mood disorders in dry eye disease and allied irritating ocular diseases Sci. Rep., 6 (2016), p. 22480

Ayaki, M. Kawashima, K. Negishi, T. Kishimoto, M. Mimura, K. Tsubota Sleep and mood disorders in women with dry eye disease Sci. Rep., 6 (2016), p. 35276

Ayaki, M. Kawashima, K. Negishi, K. Tsubota High prevalence of sleep and mood disorders in dry eye patients: survey of 1,000 eye clinic visitors Neuropsychiatric Dis. Treat., 11 (2015), pp. 889-894

Ayaki, N. Tachi, Y. Hashimoto, M. Kawashima, K. Tsubota, K. Negishi Diurnal variation of human tear meniscus volume measured with tear strip meniscometry self-examination PloS One, 14 (2019) Ban et al., 2011

Ban, Y. Ogawa, O.M. Ibrahim, Y. Tatematsu, M. Kamoi, M. Uchino, S. Yaguchi, M. Dogru, K. Tsubota Morphologic evaluation of meibomian glands in chronic graft-versus-host disease using in vivo laser confocal microscopy Mol. Vis., 17 (2011), pp. 2533-2543

Borchman et al., 2009 D. Borchman, G.N. Foulks, M.C. Yappert, J. Mathews, K. Leake, J. Bell Factors affecting evaporation rates of tear film components measured in vitro Eye Contact Lens, 35 (2009), pp. 32-37

Bron et al., 2017 A.J. Bron, C.S. de Paiva, S.K. Chauhan, S. Bonini, E.E. Gabison, S. Jain, E. Knop, M. Markoulli, Y. Ogawa, V. Perez, Y. Uchino, N. Yokoi, D. Zoukhri, D.A. Sullivan TFOS DEWS II pathophysiology report

Ocul. Surf., 15 (2017), pp. 438-510 F.W. Campbell, J.G. Robson, G. Westheimer Fluctuations of accommodation under steady viewing conditions Physiol., 145 (1959), pp. 579-594

G.L. Cennamo, A. Del Prete, R. Forte, G. Cafiero, S. Del Prete, D. Marasco Impression cytology with scanning electron microscopy: a new method in the study of conjunctival microvilli Eye, 22 (2008), pp. 138-143

Cirillo et al., 2010  G. Cirillo, C. Cavaliere, M.R. Bianco, A. De Simone, A.M. Colangelo, S. Sellitti, L. Alberghina, M. Papa Intrathecal NGF administration reduces reactive astrocytosis and changes neurotrophin receptors expression pattern in a rat model of neuropathic pain Cell. Mol. Neurobiol., 30 (2010), pp. 51-62

Colangelo et al., 2008 A.M. Colangelo, M.R. Bianco, L. Vitagliano, C. Cavaliere, G. Cirillo, L. De Gioia, D. Diana, D. Colombo, C. Redaelli, L. Zaccaro, G. Morelli, M. Papa, P. Sarmientos, L. Alberghina, E. Martegani A new nerve growth factor-mimetic peptide active on neuropathic pain in rats Neurosci., 28 (2008), pp. 2698-2709

Cowlen et al., 2003  M.S. Cowlen, V.Z. Zhang, L. Warnock, C.F. Moyer, W.M. Peterson, B.R. Yerxa Localization of ocular P2Y2 receptor gene expression by in situ hybridization Exp. Eye Res., 77 (2003), pp. 77-84

Craig et al., 2015 J.P. Craig, Y.H. Chen, P.R. Turnbull Prospective trial of intense pulsed light for the treatment of meibomian gland dysfunction Invest. Ophthalmol. Vis. Sci., 56 (2015), pp. 1965-1970

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