Depression and Dry Eyes. The Ultimate Treatment

Chronic dry eyes cause depression. Psychiatric depressions also cause dry eyes. Double edge sword.

Common dry eye symptoms such as eye pain, blurry vision, headaches, light sensitivity make daily life a struggle for many people. On the other hand, depression itself causes chronic dry eyes.  

What kind of depression causes dry eyes?

Doctors have noticed that people being treated for depression also have dry eyes. Mental health diagnoses, such as post-traumatic stress disorder and depression are linked to an increased risk of dry eye syndrome. 

The good news? There is a way to relieve dry eye symptoms naturally with TheraLife.   

Dry Eye treatment for people with depression.

TheraLife Eye capsule is an oral dry eye treatment for people with depression. TheraLife’s approach to dry eye treatment is through revitalizing internal cellular functions to promote normal tear productions. All-natural formula with little cross interactions to other medications. To learn more, click here.

Customer Stories

Research Studies on Dry Eye Disease and Depression

One study looked at nearly half a million patients. The study found that patients who suffered from dry eye disease also suffered from anxiety or depression almost 3 times more than patients who did not have these psychiatric issues.

A second study showed by the National Center for Biotechnology Information showed a direct correlation between anxiety and depression. Eighty-nine (89%) subjects diagnosed with dry eye syndrome (DES) were studied. People complete several questionnaires about anxiety, depression, and ocular surface disease., The study found that people with anxiety and depression had more dry eye symptoms than people who did not suffer from anxiety and depression.

In fact, research studies published show a connection between depression and dry eye disease. This included a report published in Cornea that found a significant difference in dry eye symptoms for those who suffered from depression and those who did not. Another study published in March showed a statistically significant link between dry eye disease and those who have depression and anxiety.  

One observational study compared dry eye symptoms with psychiatric symptoms. Results indicated that depression and anxiety were related to the subjective symptoms of dry eye disease but not the objective signs. There is a correlation between psychiatric symptoms and the prognosis of dry eye disease. This may be due to the sample selection of this study because most people in the study had a long history of dry eye disease. 

Why depression causes dry eyes?

The common consensus for the link between dry eye syndrome and depression is treating depression. Certain anti-depressants have been found to cause dry eyes. Medications with anticholinergic effects block acetylcholine in the brain. While effective in treating depression symptoms, these medications are known to be drying to the ocular surface.

Another link is how dry eyes can make depression worse. When people have problems with daily life due to dry eye, they have less participation in daily activities. This limitation inactivity leads to a decrease in the quality of life, which can lead to social withdrawal and emotional strain.

Another important link between depression and dry eye is the stress hormones constrict blood vessels that supply blood and nutrients to the whole body, including the eyes. The stress hormones also fuel inflammation – the root cause of many illnesses, including chronic dry eyes.

Some eye doctors think the link between dry eyes and psychiatric medications that are used to treat depression. They noticed that the drugs used to treat depression can make dry eye symptoms worse. Then the underlying mechanisms that cause depression, such as metabolic or hormonal imbalances, can cause dry eye disease.  

People who suffer from dry eyes are almost 3 times more likely to have depressive symptoms.

Dry Eye Symptoms

If you suffer from typical dry eye symptoms, TheraLife can naturally help calm and correct dry eye symptoms. Some common dry eye symptoms include:

• Itchy eyelids, eyes,
• Dryness
• Burning
• Sandy-gritty feeling that worsens as the day goes on.
• Scratchy feeling
• Stinging
• Tired eyes
• Eye pain
• Red eyes – could be ocular rosacea for people who have facial rosacea.
• Pulling sensation
• Pressure behind the eye – could also be glaucoma.
• Sensitivity to bright light (Photophobia). This is a hallmark of chronic dry eyes.

Dry Eye Treatment from TheraLife

As a chronic dry eye relief leader, the entire line of TheraLife products helps patients with dry eyes and depression find relief from the symptoms associated with dry eyes. 

TheraLife addresses the fundamental cause of dry eyes, underactive tear secretion with their line of all-natural products.

• TheraLife Eye Enhanced – Clinically proven to provide relief in 80% of first-time users with chronic dry eye relief, TheraLife Eye Enhanced restores the eye’s ability to produce tears naturally.
• TheraLife Eye Enhanced Starter Kit – Everything you need to provide dry eye relief. The starter kit contains 4 bottles of TheraLife Eye Enhanced, 1 bottle of Omega-3 Fish Oil, 1 Eye Lid Cleanser, and 1 Hot Compress.

Don’t suffer from dry eyes another day. Order your TheraLife Eye starter kit and find relief naturally.

Call us toll-free at 1-877-917-1989 US/Canada. International call 650-949-6080

References

1. Stapleton F, Alves M, Bunya VY, et al. TFOS DEWS II Epidemiology Report. Ocul Surf. 2017;15:334–365.
2. Gayton JL. Etiology, prevalence, and treatment of dry eye disease. Clin Ophthalmol. 2009;3:405–412.
3. Moss S, Klein R, Klein B. Prevalence of and risk factors for dry eye syndrome. Arch Ophthalmol. 2000;118:1264–1268.
4. Craig JP, Nichols KK, Nichols JJ, et al. TFOS DEWS II definition and classification report. Ocul Surf. 2017;15:276–283.
5. Tsubota K, Yokoi N, Shimazaki J, et al. New perspectives on dry eye definition and diagnosis: a consensus report by the Asia Dry Eye Society. Ocul Surf. 2017;15:65–76.
6. Van der Vaart R, Weaver MA, Lefebvre C, Davis RM. The association between dry eye disease and depression and anxiety in a large population-based study. Am J Ophthalmol. 2015;159(3):470–474.
7. Galor A, Feuer W, Lee DJ, et al. Depression, post-traumatic stress disorder, and dry eye syndrome: a study utilizing the National United States veterans affairs administrative database. Am J Ophthalmol. 2012;154:340–346.e2.
8. Wen W, Wu Y, Chen Y, et al. Dry eye disease in patients with depressive and anxiety disorders in Shanghai. Cornea. 2012;31:686–692.
9. Chia EM, Mitchell P, Rochtchina E, Lee AJ, Maroun R, Wang JJ. Prevalence and associations of dry eye syndrome in an older population: the Blue Mountains Eye Study. Clin Exp Ophthalmol. 2003;31:229–232.
10. Lee AJ, Lee J, Saw S-M, et al. Prevalence and risk factors associated with dry eye symptoms: a population based study in Indonesia. Br J Ophthalmol. 2002;86:1347–1351.
11. Jie Y, Xu L, Wu YY, Jonas JB. Prevalence of dry eye among adult Chinese in the Beijing Eye Study. Eye. 2009;23:688–693.
12. Liyue H, Chiang PP-C, Sung SC, Tong L. Dry eye-related visual blurring and irritative symptoms and their association with depression and anxiety in eye clinic patients. Curr Eye Res. 2016;41:590–599.
13. Hallak JA, Tibrewal S, Jain S. Depressive symptoms in patients with dry eye disease: a case-control study using the beck depression inventory. Cornea. 2015;34:1545–1550
14. Na K, Han K, Park Y. Depression, stress, quality of life, and dry eye disease in korean women: a population-based study. Cornea. 2015;34:733–738.
15. Yilmaz U, Gokler ME, Unsal A. Dry eye disease and depression-anxiety-stress: a hospital-based case control study in Turkey. Pakistan J Med Sci. 2015;31:626–631.
16. Szakáts I, Sebestyén M, Németh J, Birkás E, Purebl G. The role of health anxiety and depressive symptoms in dry eye disease. Curr Eye Res. 2016;41:1044–1049.
17. Li M, Gong L, Sun X, Chapin WJ. Anxiety and depression in patients with dry eye syndrome. Curr Eye Res. 2011;36:1–7.
18. Shimazaki J Definition and diagnosis of dry eye 2006 [in Japanese] Atarashii Ganka[Journal of the Eye] 2007;24:181–184.
19. Sheehan DV, Lecrubier Y, Sheehan KH, et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59(Suppl 20):22–33.
20. Takahashi N, Tomita K, Higuchi T, Inada T. The inter-rater reliability of the Japanese version of the Montgomery–Asberg depression rating scale (MADRS) using a structured interview guide for MADRS (SIGMA) Hum Psychopharmacol Clin Exp. 2004;19:187–192.
21. Rush AJ, Trivedi MH, Ibrahim HM, et al. The 16-item quick inventory of depressive. Biol Psychiatry. 2003;54:573–583
22. Otsubo T, Kudo R, Takashio O, et al. Reliability and validity of the Japanese version of Hamilton Anxiety Rating Scale-Interview Guide. Japanese J Clin Psychopharmacol. 2005;8:1579–1593.
23. Otsubo T, Tanaka K, Koda R, et al. Reliability and validity of Japanese version of the Mini-International Neuropsychiatric Interview. Psychiatry Clin Neurosci. 2005;59:517–526.
24. Montgomery A, Asberg M. A new depression scale designed to be sensitive to change. Brit J Psychiat. 1979;134:382–389
25. Fujisawa D, Nakagawa ATM. Cross-cultural adaptation of the Quick Inventory of Depressive Symptomatology-Self Report (QIDS-SR-J) Jpn J Stress Sci. 2010;25:43–52.
26. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol. 1959;32:50–55.
27. Sakane Y, Yamaguchi M, Yokoi N, et al. Development and validation of the dry eye–related quality-of-life score questionnaire. JAMA Ophthalmol. 2013;131:1331–1338
28. Wan KH, Chen LJ, Young AL. Depression and anxiety in dry eye disease: a systematic review and meta-analysis. Eye. 2016;30:1558–1567.
29. Kim KW, Han SB, Han ER, et al. Association between depression and dry eye disease in an elderly population. Invest Ophthalmol Vis Sci. 2011;52:7954–7958.
30. Mrugacz M, Ostrowska L, Bryl A, Szulc A, Zelazowska-Rutkowska B, Mrugacz G. Pro-inflammatory cytokines associated with clinical severity of dry eye disease of patients with depression. Adv Med Sci. 2017;62:338–344.
31. Kawashima M, Yamada M, Suwaki K, et al. A clinic-based survey of clinical characteristics and practice pattern of dry eye in Japan. Adv Ther. 2017;34:732–743.
32. Kang H-J, Kim S-Y, Bae K-Y, et al. Comorbidity of depression with physical disorders: research and clinical implications. Chonnam Med J. 2015;51:8–18.
33. Alderson SL, Foy R, Glidewell L, McLintock K, House A. How patients understand depression associated with chronic physical disease – a systematic review. BMC Fam Pract. 2012;13:41.
34. Moss S, Klein R, Klein B. Incidence of dry eye in an older population. Arch Ophthalmol. 2004;122:369–373.
35. Labbé A, Wang YX, Jie Y, Baudouin C, Jonas JB, Xu L. Dry eye disease, dry eye symptoms and depression: the Beijing Eye Study. Br J Ophthalmol. 2013;97:1399–1403.
36. Kawashima M, Uchino M, Yokoi N, et al. Associations between subjective happiness and dry eye disease: a new perspective from the Osaka study. PLoS One. 2015;10:1–11.
37. Chhadva P, Lee T, Sarantopoulos CD, et al. Human tear serotonin levels correlate with symptoms and signs of dry eye. Ophthalmology. 2015;122:1675–1680.
38. Imada T, Nakamura S, Hisamura R, et al. Serotonin hormonally regulates lacrimal gland secretory function via the serotonin type 3a receptor. Sci Rep. 2017;7:6965.
39. Lambiase A, Micera A, Sacchetti M, Cortes M, Mantelli F, Bonini S. Alterations of tear neuromediators in dry eye disease. Arch Ophthalmol. 2011;129:981–986.
40. Ayaki M, Kawashima M, Negishi K, Tsubota K. High prevalence of sleep and mood disorders in dry eye patients: survey of 1,000 eye clinic visitors. Neuropsychiatr Dis Treat. 2015;11:889–894.
41. Zheng Y, Wu X, Lin X, Lin H. The Prevalence of depression and depressive symptoms among eye disease patients: a systematic review and meta-analysis. Sci Rep. 2017;7:46453.